14 Jan 2026
Surrey Combatting Drugs partnership have shared information received from OHID regarding potential high risk cocaine in circulation in the Hillingdon area. A large amount of white powder, originally thought to be cocaine was tested forensically, with results confirming that the substance contained no cocaine, but did contain Methoxetamine (MXE) commonly referred to as ‘mexxy’. It has yet to be confirmed which area this substance was being sold in.
Methoxetamine is generally sold as a white powder and is chemically related to dissociative anaesthetics like ketamine and Phencyclidine (PCP), with similar effects.
The effects of MXE tend to be similar to Ketamine effects, but are more intense and longer lasting and include:
Feeling very chilled out, relaxed and euphoric. Some users have said that they feel ‘enlightened’ when taking MXE. Others have reported being agitated.
A feeling of ‘floating away’, as if the mind and body are separated (called a ‘dissociative state’). You could feel completely detached from your body and surroundings, putting yourself in danger of accidentally being hurt or being hurt by others.
Hallucinations.
Overdose.
Tachycardia and increased blood pressure.
Involuntary eye movement, loss of balance, unsteady on feet and slurred speech.
Methoxetamine is not an opioid, so naloxone will not reverse its effects. However, because it is often mixed with opioids, naloxone should still be administered in a suspected overdose, as it can reverse the opioid component and may still save a life.
Share this alert with those who might use similar substances or work with those who do, and encourage them to seek help and advice. Ensure those who need to be are aware of the signs of overdose and the appropriate emergency response, including the use of naloxone where indicated. Report any unusual drug-related presentations or adverse reactions through local reporting channels. Stay alert and share this information.
Raising awareness can prevent harm and save lives.
